Interactive Simulations
Simulation 1
An example of an explorable simulation, as depicted in Figure 1b. Drag the sliders to
change parameters in this simulation of a migrating cell; see (Niculescu et al., 2015)
for details on the model used.
Simulation 2
Interactive version of the ”Game of Life” simulation in Figure 1c. This classic model by
John Conway is a Cellular Automaton (CA), in which pixels switch between two states (0-1)
according to the number of neighbouring pixels in state 1.
Simulation 3
Interactive version of the ”Cell migration” simulation in Figure 1c. This model once
again depicts a migrating cell as defined in (Niculescu et al., 2015), but now lets the
cell migrate between two obstacles.
Simulation 4
Interactive version of the ”Cell sorting” simulation in
Figure 1c. This classic model was the first CPM as developed by Graner and Glazier
(Graner and Glazier, 1992). It contains two types of cells, and the adhesion between
neighbouring cells depends on their type. This results in spontaneous sorting of the
two mixed cell populations, as is visible in this simulation.
Simulation 5
Interactive version of the ”Dividing cells” simulation in Figure 1c. In this model,
cells have a probability of dividing after each step of the CPM simulation.
Simulation 6
Interactive simulation of ”collective migration”. This simulation is an extension of
Interactive Simulation S1, but now contains more than one cell and allows users to tune
more different CPM parameters. See also Application S1. This simulation also serves as
an example of how interactive CPM simulations can be used to tune parameters.